Pages

Liebeskind-Srogl coupling: forming C-C bond from thioester and boronic acid

Some time ago came to Lausanne Prof. Lanny S. Liebeskind from Emory University in Atlanta, co-inventor of the Liebeskind-Srogl coupling. This coupling allows the formation of a new C-C bond starting from a thioester and a boronic acid. The reaction usually requires catalytical palladium as well as a copper-based co-catalyst, but a variation using only [...]